The contributions of lesion laterality and lesion volume to decision-making impairment following frontal lobe damage

@article{Clark2003TheCO,
  title={The contributions of lesion laterality and lesion volume to decision-making impairment following frontal lobe damage},
  author={L. Clark and F. Manes and N. Antoun and B. Sahakian and T. Robbins},
  journal={Neuropsychologia},
  year={2003},
  volume={41},
  pages={1474-1483}
}
Lesions to prefrontal cortex (PFC) in humans can severely disrupt everyday decision-making, with concomitant effects on social and occupational functioning. Forty-six patients with unilateral lesions to prefrontal cortex and 21 healthy control subjects were administered three neuropsychological measures of decision-making: the Iowa Gambling Task, the Cambridge Gamble Task, and the Risk Task. Magnetic resonance imaging (MRI) scans were acquired from 40 patients, with region of interest (ROI… Expand
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