The contribution of single synapses to sensory representation in vivo.

@article{Arenz2008TheCO,
  title={The contribution of single synapses to sensory representation in vivo.},
  author={Alexander Arenz and R Angus Silver and Andreas T Schaefer and Troy W. Margrie},
  journal={Science},
  year={2008},
  volume={321 5891},
  pages={977-80}
}
The extent to which synaptic activity can signal a sensory stimulus limits the information available to a neuron. We determined the contribution of individual synapses to sensory representation by recording excitatory postsynaptic currents (EPSCs) in cerebellar granule cells during a time-varying, quantifiable vestibular stimulus. Vestibular-sensitive synapses faithfully reported direction and velocity, rather than position or acceleration of whole-body motion, via bidirectional modulation of… CONTINUE READING
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