The contribution of platelet-derived growth factor, transforming growth factor-beta1, and insulin-like growth factor-I in platelet-rich plasma to the proliferation of osteoblast-like cells.

@article{Ogino2006TheCO,
  title={The contribution of platelet-derived growth factor, transforming growth factor-beta1, and insulin-like growth factor-I in platelet-rich plasma to the proliferation of osteoblast-like cells.},
  author={Yoichiro Ogino and Yasunori Ayukawa and Toshio Kukita and Kiyoshi Koyano},
  journal={Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics},
  year={2006},
  volume={101 6},
  pages={724-9}
}
The aim of this study was to investigate the effect of platelet-rich plasma (PRP) on the proliferation of osteoblast-like cells in vitro. PRP was prepared using a centrifuge; the number of platelets (n = 32) and the levels of platelet-derived growth factor-AB (PDGF-AB), transforming growth factor-beta1 (TGF-beta1), and insulin-like growth factor-I (IGF-I) were measured (n = 16). For the proliferation assay, SaOS-2 was cultured in the presence of platelet-poor plasma (PPP), whole blood, or PRP… CONTINUE READING
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