The contribution of neurocognitive functioning to quality of life after childhood acute lymphoblastic leukemia

@article{KuninBatson2014TheCO,
  title={The contribution of neurocognitive functioning to quality of life after childhood acute lymphoblastic leukemia},
  author={Alicia Kunin-Batson and Nina S Kadan-Lottick and Joseph P Neglia},
  journal={Psycho‐Oncology},
  year={2014},
  volume={23}
}
Neurocognitive late effects after childhood acute lymphoblastic leukemia (ALL) are well‐documented, but their impact on quality of life (QOL) is not well understood. In this multi‐site study, we examined the relative influence of neurocognitive functioning, steroid randomization (prednisone vs. dexamethasone), and demographic characteristics on QOL in first‐remission survivors of childhood ALL. 
Neurocognitive Late Effects of Chemotherapy in Survivors of Acute Lymphoblastic Leukemia: Focus on Methotrexate.
  • E. van der Plas, B. Nieman, +4 authors R. Schachar
  • Medicine
  • Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent
  • 2015
TLDR
A review describes adverse neurocognitive outcomes observed in survivors of acute lymphoblastic leukemia (ALL) and discusses genetic variability in biochemical pathways targeted by chemotherapeutic agents as a possible mechanism contributing to psychopathology in ALL survivors. Expand
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  • Medicine
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  • 2016
TLDR
Survivors of childhood acute lymphoblastic leukemia treated with CNS-directed chemotherapy remain at elevated risk for attention problems that impact real-world functioning and neurocognitive function is largely age appropriate two years after chemotherapy-only treatment. Expand
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