The contribution of direct TLR signaling to T cell responses.

  title={The contribution of direct TLR signaling to T cell responses.},
  author={Adeeb H Rahman and Devon K Taylor and Laurence A Turka},
  journal={Immunologic research},
  volume={45 1},
It is well established that Toll-like receptors (TLRs) play a critical role in the generation of innate immune responses and thereby also play an important, indirect role in the initiation of subsequent adaptive T cell responses. However, T cells also express certain TLRs, and we have focused on the physiological importance of direct TLR signaling in T cells. TLRs can function as co-stimulatory receptors that complement TCR-induced signals to enhance effector T cell proliferation, survival and… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 35 extracted citations

Similar Papers

Loading similar papers…