The contribution of SNAT1 to system A amino acid transporter activity in human placental trophoblast

  title={The contribution of SNAT1 to system A amino acid transporter activity in human placental trophoblast},
  author={Michelle Desforges and S L Greenwood and J Glazier and M. Westwood and C P Sibley},
  booktitle={Biochemical and biophysical research communications},
UNLABELLED System A-mediated amino acid transport across the placenta is important for the supply of neutral amino acids needed for fetal growth. All three system A subtypes (SNAT1, 2, and 4) are expressed in human placental trophoblast suggesting there is an important biological role for each. Placental system A activity increases as pregnancy progresses, coinciding with increased fetal nutrient demands. We have previously shown SNAT4-mediated system A activity is higher in first trimester… CONTINUE READING


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