The contrasting effects of ad libitum and restricted feeding of a diet very high in saturated fats on sex ratio and metabolic hormones in mice.

@article{Alexenko2007TheCE,
  title={The contrasting effects of ad libitum and restricted feeding of a diet very high in saturated fats on sex ratio and metabolic hormones in mice.},
  author={Andrei P. Alexenko and Jiude Mao and Mark R. Ellersieck and Angela Marie Davis and Jeffrey J. Whyte and Cheryl S Rosenfeld and R Michael Roberts},
  journal={Biology of reproduction},
  year={2007},
  volume={77 4},
  pages={
          599-604
        }
}
Skewing of the sex ratio towards males occurs among pups born to mice fed a very high saturated fat (VHF) diet. In the present study, we tested whether the fat content of the VHF diet rather than the number of calories consumed is responsible for this effect. Eight-week-old NIH Swiss mice were placed on the VHF diet either ad libitum (VHF) or in a restricted manner (VHF-R). The VHF-R mice gained weight at a similar rate to controls fed a standard chow diet. Mice were bred at 15 wk and… CONTINUE READING

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