The continuum/spectrum concept of mood disorders: is mixed depression the basic link?

  title={The continuum/spectrum concept of mood disorders: is mixed depression the basic link?},
  author={Franco Benazzi},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
  • F. Benazzi
  • Published 7 September 2006
  • Psychology, Medicine
  • European Archives of Psychiatry and Clinical Neuroscience
BackgroundMixed states, i.e., opposite polarity symptoms in the same mood episode, question the bipolar/unipolar splitting of mood disorders, and support a spectrum view. Study aim was assessing the distribution of intradepressive hypomanic symptoms between bipolar-II (BP-II) and major depressive disorder (MDD) depressions, and testing a dose–response relationship between number of intradepressive hypomanic symptoms and bipolar family history. No bi-modality, and a dose–response relationship… 

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