The conserved tetrameric subunit stoichiometry of Slc26 proteins.

@article{Hallworth2013TheCT,
  title={The conserved tetrameric subunit stoichiometry of Slc26 proteins.},
  author={Richard Hallworth and Kelsey Stark and Lyandysha V Zholudeva and Benjamin B. Currall and Michael G. Nichols},
  journal={Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada},
  year={2013},
  volume={19 4},
  pages={799-807}
}
The Slc26 family proteins, with one possible exception, transport anions across membranes in a wide variety of tissues in vertebrates, invertebrates, and plants. Mutations in human members of the family are a significant cause of disease. Slc26 family proteins are thought to be oligomers, but their stoichiometry of association is in dispute. A recent study, using sequential bleaching of single fluorophore-coupled molecules in membrane fragments, demonstrated that mammalian Slc26a5 (prestin) is… CONTINUE READING