The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation

@article{Hori2015TheCW,
  title={The conserved Wdr8-hMsd1/SSX2IP complex localises to the centrosome and ensures proper spindle length and orientation},
  author={Akiko Hori and A. Morand and C. Ikebe and D. Frith and A. Snijders and T. Toda},
  journal={Biochemical and Biophysical Research Communications},
  year={2015},
  volume={468},
  pages={39 - 45}
}
The centrosome plays a pivotal role in a wide range of cellular processes and its dysfunction is causally linked to many human diseases including cancer and developmental and neurological disorders. This organelle contains more than one hundred components, and yet many of them remain uncharacterised. Here we identified a novel centrosome protein Wdr8, based upon the structural conservation of the fission yeast counterpart. We showed that Wdr8 constitutively localises to the centrosome and super… Expand
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