The conformation and CETP inhibitory activity of [10]-dehydrogingerdione isolated from Zingiber officinale.

Abstract

In the course of searching for cholesteryl ester transfer protein (CETP) inhibitors from natural sources, a new type of CETP inhibitor, [10]-dehydrogingerdione (1), was isolated from the extract of rhizomes of Zingiber officinale Roscoe. By NMR spectroscopic analysis of its (1)HNMR, (13)C-NMR, and (1)H-(1)H COSY, HMBC, HMQC and NOESY, more precise structure… (More)
DOI: 10.1007/s12272-011-0505-5

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