The concentration-dependent disposition and kinetics of inulin

@article{Prescott1991TheCD,
  title={The concentration-dependent disposition and kinetics of inulin},
  author={Laurie Prescott and J. A. Neil McAuslane and Stephen Freestone},
  journal={European Journal of Clinical Pharmacology},
  year={1991},
  volume={40},
  pages={619-624}
}
SummaryThe disposition of inulin was studied in 30 healthy male and 10 healthy female volunteers, and 10 patients with stable chronic renal failure (mean creatinine clearance 45 ml·min−1) following intravenous infusion of 70 mg·kg−1 over 5 min.Plasma concentrations fell rapidly initially but the rate of decline decreased continuously over 8 h and a linear terminal elimination phase could not be identified. Inulin was excreted rapidly by the subjects with normal renal function and 97.3% of the… CONTINUE READING

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The pharmacokinetics of the interstitial space in humans

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