The composite nanomaterials containing (R)-thalidomide-molecularly imprinted polymers as a recognition system for enantioselective- controlled release and targeted drug delivery

@article{Suksuwan2015TheCN,
  title={The composite nanomaterials containing (R)-thalidomide-molecularly imprinted polymers as a recognition system for enantioselective- controlled release and targeted drug delivery},
  author={Acharee Suksuwan and Luelak Lomlim and T. Rungrotmongkol and T. Nakpheng and F. Dickert and R. Suedee},
  journal={Journal of Applied Polymer Science},
  year={2015},
  volume={132}
}
A molecularly imprinted polymer (MIP) enantioselective receptor for the (R)-thalidomide enantiomer was synthesized and evaluated for its ability to deliver the drug to cancer cells. Polymer networks with precisely engineered binding sites were built into the assembled nanoparticles by a self-organizing template in the prepolymerized mixture using methacrylic acid, a fluorescently active 2,6-bis(acrylamido)pyridine and N,N 0 methylene-bis-acrylamide, via both a covalent approach and a physical… Expand
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Molecularly Imprinted Materials for Selective Biological Recognition.
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