The complexity of drug development for irritable bowel syndrome

@article{Kamm2002TheCO,
  title={The complexity of drug development for irritable bowel syndrome},
  author={M. Kamm},
  journal={Alimentary Pharmacology & Therapeutics},
  year={2002},
  volume={16}
}
  • M. Kamm
  • Published 2002
  • Medicine
  • Alimentary Pharmacology & Therapeutics
  • Drug development for functional gastrointestinal disorders is complex. These conditions involve central and peripheral physiological changes, together with psychological factors. Methodological problems have included a poor appreciation of the physiological and psychological correlates of patients' symptoms, a lack of animal models of proven relevance, and safety issues. Government, patient pressure groups and the Internet can also influence a drug's success. Most recent interest has focused on… CONTINUE READING
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