• DOI:10.1046/j.1365-2036.2002.01185.x
Corpus ID: 24133545

The complexity of drug development for irritable bowel syndrome

@article{Kamm2002TheCO,
  title={The complexity of drug development for irritable bowel syndrome},
  author={M. Kamm},
  journal={Alimentary Pharmacology & Therapeutics},
  year={2002},
  volume={16}
}

M. Kamm

Published 2002

Medicine

Alimentary Pharmacology & Therapeutics

Drug development for functional gastrointestinal disorders is complex. These conditions involve central and peripheral physiological changes, together with psychological factors. Methodological problems have included a poor appreciation of the physiological and psychological correlates of patients' symptoms, a lack of animal models of proven relevance, and safety issues. Government, patient pressure groups and the Internet can also influence a drug's success. Most recent interest has focused on… CONTINUE READING

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