The complexity of DRw6 and DR5 haplotypes in American blacks demonstrated by serology, cellular typing, and restriction fragment length polymorphism analysis.

@article{Lee1990TheCO,
  title={The complexity of DRw6 and DR5 haplotypes in American blacks demonstrated by serology, cellular typing, and restriction fragment length polymorphism analysis.},
  author={K W Lee and Carolyn K Hurley and Robert J. Hartzman and A H Johnson},
  journal={Human immunology},
  year={1990},
  volume={29 3},
  pages={202-19}
}
  • K W Lee, Carolyn K Hurley, +1 author A H Johnson
  • Published 1990 in Human immunology
This study describes the diversity of DRw6 and DR5 haplotypes in the American black population using serology, cellular typing, and restriction fragment length polymorphism (RFLP) analysis. DRw6 (DRw13 and DRw14) and DR5 (DRw11 and DRw12) haplotypes are observed at a high frequency in this population (DRw6: 32%, DR5: 30%). Many of these haplotypes express undefined HLA-D specificities and unusual DQ and DRw52 associations which previously have not been well characterized or reported (e.g… CONTINUE READING