The complex language of chromatin regulation during transcription

  title={The complex language of chromatin regulation during transcription},
  author={Shelley L Berger},
An important development in understanding the influence of chromatin on gene regulation has been the finding that DNA methylation and histone post-translational modifications lead to the recruitment of protein complexes that regulate transcription. Early interpretations of this phenomenon involved gene regulation reflecting predictive activating or repressing types of modification. However, further exploration reveals that transcription occurs against a backdrop of mixtures of complex… CONTINUE READING
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