The complex interplay among factors that influence allelic association

  title={The complex interplay among factors that influence allelic association},
  author={Krina T Zondervan and Lon R. Cardon},
  journal={Nature Reviews Genetics},
Since the initial excitement surrounding the sequencing of the human genome, there has been a continuing debate on how this wealth of information can be used to investigate the genetic contribution to common complex diseases — at present, the principal health burden in the Western world. COMPLEX TRAITS arise as a result of the interplay between many genetic variants and environmental exposures. Tracing patterns of gene segregation in families — previously used successfully for single-gene… CONTINUE READING
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