The complex genetic architecture of Drosophila life span.

@article{Leips2002TheCG,
  title={The complex genetic architecture of Drosophila life span.},
  author={Jeff Leips and Trudy F C Mackay},
  journal={Experimental aging research},
  year={2002},
  volume={28 4},
  pages={361-90}
}
Continuous phenotypic variation in life span results from segregating genetic variation at multiple loci, the environmental sensitivity of expression of these loci, and the history of environmental variation experienced by the organism throughout its life. We have mapped quantitative trait loci (QTL) that produce variation in the life span of mated Drosophila melanogaster using a panel of recombinant inbred lines (RIL) that were backcrossed to the parental strains from which they were derived… CONTINUE READING

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