The complete structure of the 55S mammalian mitochondrial ribosome

@article{Greber2015TheCS,
  title={The complete structure of the 55S mammalian mitochondrial ribosome},
  author={Basil J. Greber and Philipp Bieri and Marc Leibundgut and Alexander Leitner and Ruedi Aebersold and Daniel Boehringer and Nenad Ban},
  journal={Science},
  year={2015},
  volume={348},
  pages={303 - 308}
}
Resolving whole mitoribosomes Mitochondria probably evolved from a prokaryotic cell living within a proto-eukaryotic cell. Consequently, mitochondria have lost much of their genomic DNA, except for a few genes that require highly divergent mitoribosomes for protein translation. Greber et al. and Amunts et al. have used cryo–electron microscopy to uncover the structure of this complex (see the Perspective by Beckmann and Hermann) and reveal an unusual mRNA binding channel. The structure supplies… Expand
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