The complete sequence of the human CD79b (lgβ/B29) gene: identification of a conserved exon/intron organization, immunoglobulin-like regulatory regions, and allelic polymorphism

@article{Hashimoto2004TheCS,
  title={The complete sequence of the human CD79b (lgβ/B29) gene: identification of a conserved exon/intron organization, immunoglobulin-like regulatory regions, and allelic polymorphism},
  author={S. Hashimoto and N. Chiorazzi and P. Gregersen},
  journal={Immunogenetics},
  year={2004},
  volume={40},
  pages={145-149}
}
  • S. Hashimoto, N. Chiorazzi, P. Gregersen
  • Published 2004
  • Biology, Medicine
  • Immunogenetics
  • We determined the complete genomic sequence of the human CD79b (Igβ/B29) gene. The CD79b gene product is associated with the membrane immunoglobulin signaling complex which is composed of immunoglobulin (Ig) itself, associated in a noncovalent fashion with CD79b and a second polypeptide chain, CD79a (Igα/mb1). The sequence and exon/intron organization of the human and mouse CD79b genes are highly similar. The gene organization suggests that some variant forms of CD79b may arise by virtue of… CONTINUE READING
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