The complete genome sequence of the gastric pathogen Helicobacter pylori

@article{Tomb1997TheCG,
  title={The complete genome sequence of the gastric pathogen Helicobacter pylori},
  author={Jean-François Tomb and Owen White and Anthony R. Kerlavage and Rebecca A. Clayton and Granger G. Sutton and Robert D. Fleischmann and Karen A. Ketchum and Hans-Peter Klenk and Steven R. Gill and Brian A. Dougherty and Karen E. Nelson and John F. Quackenbush and Lixin Zhou and Ewen Kirkness and Scott N. Peterson and Brendan J. Loftus and Delwood L. Richardson and Robert J. Dodson and Hanif G. Khalak and Anna Głodek and Keith Mckenney and Lisa M. Fitzegerald and N H Lee and Mark D. Adams and Erin K. Hickey and Douglas E. Berg and Jeanine D. Gocayne and Teresa R. Utterback and Jeremy D. Peterson and Jenny M. Kelley and Matthew D. Cotton and Janice M. Weidman and Claire Y. Fujii and C Bowman and Larry Watthey and E. Wallin and William S. Hayes and Mark Borodovsky and Peter D. Karp and Hamilton O. Smith and Claire M. Fraser and J. Craig Venter},
  journal={Nature},
  year={1997},
  volume={388},
  pages={539-547}
}
Helicobacter pylori, strain 26695, has a circular genome of 1,667,867 base pairs and 1,590 predicted coding sequences. Sequence analysis indicates that H. pylori has well-developed systems for motility, for scavenging iron, and for DNA restriction and modification. Many putative adhesins, lipoproteins and other outer membrane proteins were identified, underscoring the potential complexity of host–pathogen interaction. Based on the large number of sequence-related genes encoding outer membrane… Expand
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