The complete genome sequence of Escherichia coli K-12.

@article{Blattner1997TheCG,
  title={The complete genome sequence of Escherichia coli K-12.},
  author={Frederick R. Blattner and Guy Plunkett and Craig A. Bloch and Nicole T. Perna and Valerie Burland and Monica Riley and Julio Collado-Vides and Jeremy D. Glasner and Christopher K. Rode and George F. Mayhew and Jason Gregor and Nelson Wayne Davis and Heather A. Kirkpatrick and M A Goeden and Debra J. Rose and Bob Mau and Yankun Shao},
  journal={Science},
  year={1997},
  volume={277 5331},
  pages={
          1453-62
        }
}
The 4,639,221-base pair sequence of Escherichia coli K-12 is presented. Of 4288 protein-coding genes annotated, 38 percent have no attributed function. Comparison with five other sequenced microbes reveals ubiquitous as well as narrowly distributed gene families; many families of similar genes within E. coli are also evident. The largest family of paralogous proteins contains 80 ABC transporters. The genome as a whole is strikingly organized with respect to the local direction of replication… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-8 OF 8 REFERENCES

I–Sce I is a site-specific intron-encoded homing endonuclease

A. Perrin, M. Buckle, B. Dujon, J EMBO
  • Gene 166,
  • 1995
VIEW 1 EXCERPT

Six segments of the genome were sequenced using radioactive chemistry

D. L. Daniels, G. Plunkett, V. Burland, F. R. Blattner
  • Nucleic Acids Res
  • 1994
VIEW 1 EXCERPT

resequence overlapping regions between adjacent clones, and screening to remove lambda vector sequences before sequencing

D. L. Daniels
  • 1990
VIEW 1 EXCERPT

Evolution by Gene Duplication

  • Springer Berlin Heidelberg
  • 1970
VIEW 1 EXCERPT

Proc

C. Burge, A. M. Campbell, S. Karlin
  • Natl. Acad. Sci. U.S.A. 89, 1358 (1992); M. McClelland and A. S. Bhagwat, Nature 355, 595 (1992); A. S. Bhagwat and M. McClelland, Nucleic Acids Res. 20, 1663 (1992); R. Merkl, M. Kroger, P. Rice, H. J. Fritz, ibid., p.
  • 1657
VIEW 1 EXCERPT

in (2), vol

R. M. Macnab
  • 2, pp. 123–145; M. ARTICLE www.sciencemag.org z SCIENCE z VOL. 277 z 5 SEPTEMBER 1997
  • 1461
VIEW 2 EXCERPTS

Nucleic Acids Res

K. Yoda, H. Yasuda, X. W. Xiang, T. Okazaki
  • 16, 6531 (1988); H. Hiasa et al., Gene 84, 9 (1989); K. Yoda and T. Okazaki, Mol. Gen. Genet. 227, 1 (1991); J. R. Swart and M. A. Griep, J. Biol. Chem. 268,
  • 1297
VIEW 1 EXCERPT

168, 55 (1986); T

R. P. Burlingame, L. Wyman, P. J. Chapman, J. Bacteriol
  • D. H. Bugg, Biochim. Biophys. Acta
  • 1202
VIEW 2 EXCERPTS

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