The complement system in teleosts.

  title={The complement system in teleosts.},
  author={M. Claire H. Holland and John D. Lambris},
  journal={Fish & shellfish immunology},
  volume={12 5},
Complement, an important component of the innate immune system, is comprised of about 35 individual proteins. In mammals, activation of complement results in the generation of activated protein fragments that play a role in microbial killing, phagocytosis, inflammatory reactions, immune complex clearance, and antibody production. Fish appear to possess activation pathways similar to those in mammals, and the fish complement proteins identified thus far show many homologies to their mammalian… CONTINUE READING


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