The complement system and age-related macular degeneration

@article{Sivaprasad2006TheCS,
  title={The complement system and age-related macular degeneration},
  author={Sobha Sivaprasad and Ngai Victor Chong},
  journal={Eye},
  year={2006},
  volume={20},
  pages={867-872}
}
PurposeAge-related macular degeneration (AMD) is the leading cause of blindness in the developed world. There are increasing evidences to suggest the complement system may play a significant role on the pathogenesis of AMD. In this review, we summarise the current research in this area.MethodsReview of literature.ResultsThe complement system is a complex system with several activation pathways. Complement factor H (CFH) polymorphisms has been associated with increase risk of AMD. CFH is an… CONTINUE READING

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