The comparative efficacy of stabilized stannous fluoride/sodium hexametaphosphate dentifrice and sodium fluoride/triclosan/copolymer dentifrice for the control of gingivitis: a 6-month randomized clinical study.

@article{Archila2004TheCE,
  title={The comparative efficacy of stabilized stannous fluoride/sodium hexametaphosphate dentifrice and sodium fluoride/triclosan/copolymer dentifrice for the control of gingivitis: a 6-month randomized clinical study.},
  author={Luis Archila and Robert D. Bartizek and J Leslie Winston and Aaron R. Biesbrock and Stephen F. McClanahan and Tao He},
  journal={Journal of periodontology},
  year={2004},
  volume={75 12},
  pages={
          1592-9
        }
}
BACKGROUND Antimicrobial agents such as stannous fluoride and triclosan have been incorporated into dentifrice formulations and have been shown to be effective in reducing gingivitis. The objective of this study was to compare the anti-gingivitis efficacy of a 0.454% stannous fluoride/sodium hexametaphosphate dentifrice to a positive control triclosan/copolymer dentifrice. METHODS This was a 6-month, randomized, double-masked, parallel-group study conducted according to the American Dental… 
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42 Citations
Background Citations
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Methods Citations
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Results Citations
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42 Citations

Citation Type

Citation Type

Comparative Efficacy of Stabilized Stannous Fluoride/Sodium Hexametaphosphate Dentifrice and Sodium Fluoride/Triclosan/Copolymer Dentifrice for the Prevention of Periodontitis in Xerostomic Patients: A 2-Year Randomized Clinical Trial
TLDR
This study compared the efficacy of a stannous fluoride (SnF2) dentifrice relative to a positive control triclosan dentif rice for prevention of clinical attachment loss (CAL) in xerostomic patients to compare the dentifrices for root caries remineralization.
Antigingivitis efficacy of a stabilized stannous fluoride/sodium hexametaphosphate dentifrice in subjects previously nonresponsive to a triclosan/copolymer dentifrice.
TLDR
It is demonstrated that the use of an experimental 0.454% stannous fluoride/sodium hexametaphosphate dentifrice over a 12-week period provides a statistically significant and clinically relevant effect in the control of gingivitis among subjects who previously did not respond to 6 months of use of a sodium fluoride/triclosan/copolymer dentif rice.
Evaluation of anti-gingivitis benefits of stannous fluoride dentifrice among triclosan dentifrice users.
TLDR
Both treatment groups experienced significant reductions in number of bleeding sites, gingival bleeding index (GBI), andgingival inflammation (MGI) relative to baseline (P < 0.001).
Efficacy and safety of a novel stabilized stannous fluoride and sodium hexametaphosphate dentifrice for dentinal hypersensitivity.
TLDR
The stabilized stannous fluoride + SHMP dentif Rice provided statistically significant reductions in dentinal hypersensitivity at four and eight weeks compared to the sodium fluoride control dentifrice.
Anti-gingivitis effects of a novel 0.454% stabilized stannous fluoride dentifrice relative to a positive control.
TLDR
This single-center, randomized and controlled, double-blind, parallel group, 2-month trial enrolled 200 adults with mild-to-moderate gingivitis and produced statistically significant reductions in number of bleeding sites, GBI, and MGI on average relative to pre-treatment (P< 0.0001).
Plaque control evaluation of a stabilized stannous fluoride dentifrice compared to a triclosan dentifrice in a six-week trial.
TLDR
Both dentifrices showed statistically significant reductions from baseline in whole mouth, gumline, and interproximal accumulated overnight plaque after three and six weeks of brushing, but the SnF2 dentifrice showed statistically significantly greater plaque reductions versus the triclosan dentif Rice.
Assessment of the effects of a stannous fluoride dentifrice on gingivitis in a two-month positive-controlled clinical study.
TLDR
An advanced stannous fluoride test dentifrice provided superior reductions in gingival inflammation and gingivitis compared to a commercially available triclosan/copolymer positive-control dentif Rice after two months of tooth brushing.
A controlled 6-month clinical trial to study the effects of a stannous fluoride dentifrice on gingivitis.
TLDR
Twice daily use of the SnF(2)/SHMP dentifrice over 6 months provided statistically significant anti-plaque and anti-gingivitis benefits relative to a negative control.
Sustained antibacterial actions of a new stabilized stannous fluoride dentifrice containing sodium hexametaphosphate.
TLDR
Findings confirm the long-lasting antibacterial action of the new stannous fluoride dentifrice, which serves as a basis for its therapeutic benefits.
A randomized clinical trial to compare plaque inhibition of a sodium fluoride/potassium nitrate dentifrice versus a stabilized stannous fluoride/sodium hexametaphosphate dentifrice.
TLDR
The SnF2/SHMP dentifrice (blend-a-med EXPERT GUMS PROTECTION) inhibits plaque regrowth both overnight and during the day to a significantly greater degree than the NaF/KNO3 dentif Rice (Sensodyne ProNamel).
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TLDR
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TLDR
It is demonstrated that over a six-month period, twice-daily use of a dentif Rice containing 0.454% stabilized stannous fluoride significantly reduced gingivitis and gingival bleeding, relative to a 0.243% sodium fluoride control dentifrice.
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