The common, Near‐Eastern origin of Ashkenazi and Sephardi Jews supported by Y‐chromosome similarity

@article{Benerecetti1993TheCN,
  title={The common, Near‐Eastern origin of Ashkenazi and Sephardi Jews supported by Y‐chromosome similarity},
  author={A. S. Santachiara Benerecetti and Ornella Semino and Giuseppe Passarino and Antonio Torroni and Radim Brdi{\vc}ka and M. Fellous and Guido Modiano},
  journal={Annals of Human Genetics},
  year={1993},
  volume={57}
}
About 80 Sephardim, 80 Ashkenazim and 100 Czechoslovaks were examined for the Y‐specific RFLPs revealed by the probes p12f2 and p49a, f on TaqI DNA digests. The aim of the study was to investigate the origin of the Ashkenazi gene pool through the analysis of markers which, having an exclusively holoandric transmission, are useful to estimate paternal gene flow. The comparison of the two groups of Jews with each other and with Czechoslovaks (which have been taken as a representative source of… 
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References

SHOWING 1-10 OF 27 REFERENCES
HLA polymorphism in Israel. 9. An overall comparative analysis.
TLDR
Estimates of "average" distances within major population groups suggest that the Ashkenazi Jews are a more homogeneous population than East European non-Jews or than Middle-Eastern populations (Arabs, Armenians, Lebanese and Turks).
mtDNA polymorphism in two communities of Jews.
TLDR
Twenty-one types of mtDNA were found in a survey of 39 Israeli Jews, of whom 18 were Sephardic and 21 Ashkenazic, implying that these modern Jews stem from a minimum of 21 maternal lineages that were already distinct from one another 4,000-5,000 years ago.
Y chromosome DNA polymorphisms in human populations: differences between Caucasoids and Africans detected by 49a and 49f probes
TLDR
Four new bands were observed in the 49a‐49f/71agl polymorphisms studied in 121 Africans and 125 Caucasians and three patterns were found in which bands constantly present so far (G, 0 and H‐P‐R) were missing.
Genetic diversity among Jews : diseases and markers at the DNA level
I. History and Demography: Sergio Dellapergola: Major Demographic Trends of World Jewry: The Last Hundred Years II. Polymorphisms: Kenneth K. Kidd, Judith R. Kidd, Batsheva Bonne-Tamir, Maria New:
Y chromosome probe p49a detects complex PvuII haplotypes and many new TaqI haplotypes in southern African populations.
TLDR
Clustering of the negroid and Khoisan groups is not what might have been expected from the known linguistic affinities, suggesting that the 49a/TaqI haplotype analysis of these populations is not sufficiently sensitive to distinguish between many of the populations.
Human mitochondrial DNA types in two Israeli populations--a comparative study at the DNA level.
TLDR
Variations in human mtDNA restriction endonuclease fragment patterns were investigated in a sample number of 81 Israelis--Jews and Arabs--using total blood cell DNA, finding one of the new types filled a "missing link" originally postulated in a phylogeny of mtDNA human types.
Genetic affinities of Jewish populations.
TLDR
The results of this study indicate that stochastic factors are likely to have played a role in masking the descent relationships of the J populations, and there is evidence of genetic similarity between J and corresponding NJ populations, suggesting reciprocal gene flow between these populations or convergent selection in a common environment.
The p12f2/TaqI Y-specific polymorphism in three groups of Italians and in a sample of Senegalese.
TLDR
The TaqI/p12f2 Y-specific RFLP was studied in 258 Italians and in 65 Senegalese and the two allelic fragments of 10 and 8 kb characterizing this polymorphism were both found in the Italians but only the 10 kb band was found among the SenEGalese.
Cytological differences and chromosomal rearrangements in four members of the Anopheles dirus complex (Diptera: Culicidae).
TLDR
A reference photomap of the larval salivary gland, polytene chromosomes of the Anopheles dirus complex (species A) is presented and overall banding patterns are conservative in the group: species A, B, C, and C are virtually homosequential.
HLA Polymorphism in Israel
Phenotype and gene frequencies of antigens at the A and B HLA loci were determined in a sample of 89 random Libyan Jews now settled in Israel. Most antigens at the A locus are within the range found
...
1
2
3
...