The comings and goings of a Y polymorphism

  title={The comings and goings of a Y polymorphism},
  author={Chris Tyler-Smith and Gilean McVean},
  journal={Nature Genetics},
A deletion that removes 1.6 Mb of DNA and several genes from the Y chromosome increases its carriers' chance of infertility, yet is present in ∼2% of men. The Y chromosome can no longer be regarded as a neutral locus in evolutionary studies.