The comet assay in the Phenion ® full thickness model as a putative tool for improved in vitro genotoxicity testing

Genotoxicity is one of the first toxicological endpoints to be tested within the course of safety assessment e.g. for cosmetic ingredients, pharmaceuticals, or agrochemicals. Regulation requires that cosmetic ingredients are subjected to an in vitro test battery first. The currently accepted in vitro tests exhibit high sensitivity but unfortunately low… CONTINUE READING