The combined use of Paracoccidioides brasiliensis Pb40 and Pb27 recombinant proteins enhances chemotherapy effects in experimental paracoccidioidomycosis.

@article{Fernandes2011TheCU,
  title={The combined use of Paracoccidioides brasiliensis Pb40 and Pb27 recombinant proteins enhances chemotherapy effects in experimental paracoccidioidomycosis.},
  author={Viviane Cristina Fernandes and Estef{\^a}nia Mara do Nascimento Martins and Jankerle N Boeloni and Juliana Barbosa Coitinho and Rog{\'e}ria Serakides and Alfredo de Miranda G{\'o}es},
  journal={Microbes and infection},
  year={2011},
  volume={13 12-13},
  pages={
          1062-72
        }
}
Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis (PCM), a chronic granulomatous mycosis prevalent in Latin America, and cell-mediated immunity represents the main mode of protection against this fungal infection. The conventional treatment for this mycosis involves long periods of therapy resulting in sequels and a high frequency of relapse. The search for new alternative methods of treatment is thus necessary. With this aim, the objective of this work was to… CONTINUE READING

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