The combined effects of dietary fat and estrogen on survival, 7,12-dimethylbenz(a)anthracene-induced breast cancer and prolactin metabolism in rats.

@article{Clinton1995TheCE,
  title={The combined effects of dietary fat and estrogen on survival, 7,12-dimethylbenz(a)anthracene-induced breast cancer and prolactin metabolism in rats.},
  author={Steven K. Clinton and Pi-hsueh Shirley Li and Anthony L Mulloy and Peter B. Imrey and Sunita Nandkumar and Willard J. Visek},
  journal={The Journal of nutrition},
  year={1995},
  volume={125 5},
  pages={1192-204}
}
The relationships between dietary fat concentration (10 or 40% of energy), fat source (corn oil or beef tallow) and estrogen (control, ovariectomy or ovariectomy with estrogen replacement) to 7,12-dimethylbenz(a)anthracene (DMBA)-induced breast carcinogenesis and survival in rats were studied in a 2 x 2 x 3 factorial experiment. Female Sprague-Dawley rats given DMBA (2.5 mg/100 g body wt, intragastric) at 55 d of age were randomly allocated to three groups 48 h later: sham ovariectomy (control… CONTINUE READING

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