The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats.

@article{Salman2013TheCE,
  title={The combined effect of metformin and L-cysteine on inflammation, oxidative stress and insulin resistance in streptozotocin-induced type 2 diabetes in rats.},
  author={Zenat K Salman and Rowaida Refaat and Eman A Selima and Ashgan El Sarha and M. Abdel-Hamid Ismail},
  journal={European journal of pharmacology},
  year={2013},
  volume={714 1-3},
  pages={448-55}
}
Increasing evidence has established causative links between obesity, chronic inflammation and insulin resistance; the core pathophysiological feature in type 2 diabetes mellitus. This study was designed to examine whether the combination of L-cysteine and metformin would provide additional benefits in reducing oxidative stress, inflammation and insulin resistance in streptozotocin-induced type 2 diabetes in rats. Male Wistar rats were fed a high-fat diet (HFD) for 8 weeks to induce insulin… CONTINUE READING

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Insulin resistance and type 2 diabetes

  • R. Taylor
  • Diabetes
  • 2012
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