The combined CTA1-DD/ISCOMs vector is an effective intranasal adjuvant for boosting prior Mycobacterium bovis BCG immunity to Mycobacterium tuberculosis.

@article{Andersen2007TheCC,
  title={The combined CTA1-DD/ISCOMs vector is an effective intranasal adjuvant for boosting prior Mycobacterium bovis BCG immunity to Mycobacterium tuberculosis.},
  author={Claire A. Swetman Andersen and Jes Dietrich and Else Marie Agger and Nils Y Lycke and Karin Bengtsson L{\"o}vgren and Peter Hvilsh\oj Andersen},
  journal={Infection and immunity},
  year={2007},
  volume={75 1},
  pages={408-16}
}
Infection with Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), remains one of the leading causes of mortality worldwide. The current "gold standard" vaccine Mycobacterium bovis BCG has a limited efficacy that wanes over time. The development of a vaccine to boost BCG-induced immunity is therefore a highly active area of research… CONTINUE READING