The color of mice: in the light of GFP-variant reporters

@article{Hadjantonakis2001TheCO,
  title={The color of mice: in the light of GFP-variant reporters},
  author={Anna-Katerina Hadjantonakis and Andras D Nagy},
  journal={Histochemistry and Cell Biology},
  year={2001},
  volume={115},
  pages={49-58}
}
The mouse currently represents the premier model organism for mammalian genetic studies. Over the past decade the production of targeted and transgenic lines of mice has become commonplace, with current technology allowing the creation of mutations at base pair resolution. Such genome modifications are becoming increasingly elaborate and often incorporate gene-based reporters for tagging different cellular populations. Until recently, lacZ, the bacterial beta-galactosidase gene has been the… CONTINUE READING

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