The collagen structure of the tympanic membrane: collagen types I, II, and III in the healthy tympanic membrane, during healing of a perforation, and during infection.

@article{Stenfeldt2006TheCS,
  title={The collagen structure of the tympanic membrane: collagen types I, II, and III in the healthy tympanic membrane, during healing of a perforation, and during infection.},
  author={Karin Stenfeldt and Cathrine Johansson and Sten Olof Hellstr{\"o}m},
  journal={Archives of otolaryngology--head & neck surgery},
  year={2006},
  volume={132 3},
  pages={293-8}
}
OBJECTIVE To analyze the distribution of 3 collagen types in healthy tympanic membranes, during healing of a perforation, and during infection. DESIGN Immunohistochemical study of collagen types I, II, and III in the tympanic membranes of healthy rats as well as during healing of a perforation and in the presence of infection with Streptococcus pneumoniae at various time points. SETTING Laboratory research center at a university hospital. RESULTS Type II collagen was a main constituent of… CONTINUE READING

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Collagen types I and III are present in the acute healing phase after myringotomy and infection , and the collagen content of the tympanic membrane is modified during the inflammatory and healing process .
Extensive amounts of all 3 collagen types were present in the scar tissue in the tympanic membranes of rats that had undergone myringotomy during the presence of acute otitis media .
Collagen types I and III are present in the acute healing phase after myringotomy and infection , and the collagen content of the tympanic membrane is modified during the inflammatory and healing process .
Extensive amounts of all 3 collagen types were present in the scar tissue in the tympanic membranes of rats that had undergone myringotomy during the presence of acute otitis media .
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