The cognitive-enhancing properties of modafinil are limited in non-sleep-deprived middle-aged volunteers

@article{Randall2004TheCP,
  title={The cognitive-enhancing properties of modafinil are limited in non-sleep-deprived middle-aged volunteers},
  author={Delia C. Randall and Nicola L Fleck and John Michael Shneerson and Sandra E. File},
  journal={Pharmacology Biochemistry and Behavior},
  year={2004},
  volume={77},
  pages={547-555}
}
Modafinil is a selective wakefulness-promoting agent that has been shown to enhance cognitive performance under conditions of sleep deprivation but which has equivocal effects in normal young volunteers. In a double-blind parallel group design study, 45 non-sleep-deprived middle-aged volunteers (20 men and 25 women, aged 50-67 years) were randomly allocated to receive two capsules containing placebo, 100 or 200 mg modafinil, and 3 h later they completed 100 mm visual analogue scales of mood and… CONTINUE READING
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