The coevolution of insect muscle TpnT and TpnI gene isoforms.

@article{Herranz2005TheCO,
  title={The coevolution of insect muscle TpnT and TpnI gene isoforms.},
  author={Ra{\'u}l Herranz and Jes{\'u}s G{\'o}mez Mateos and Jos{\'e} Antonio Diego M{\'a}s and Elena Garc{\'i}a-Zaragoza and M. R. Gonz{\'a}lez Cervera and R. Loures Marco},
  journal={Molecular biology and evolution},
  year={2005},
  volume={22 11},
  pages={
          2231-42
        }
}
In bilaterians, the main regulator of muscle contraction is the troponin (Tpn) complex, comprising three closely interacting subunits (C, T, and I). To understand how evolutionary forces drive molecular change in protein complexes, we have compared the gene structures and expression patterns of Tpn genes in insects. In this class, while TpnC is encoded by multiple genes, TpnT and TpnI are encoded by single genes. Their isoform expression pattern is highly conserved within the Drosophilidae, and… CONTINUE READING

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