The coding region of the human DLX6 gene contains a polymorphic CAG/CCG repeat.

@article{Pfeffer2001TheCR,
  title={The coding region of the human DLX6 gene contains a polymorphic CAG/CCG repeat.},
  author={Ulrich Pfeffer and Paola Ferro and V Pavia and Sonya Trombino and Raffaella Dell'eva and Giorgio Roberto Merlo and Giovanni Levi},
  journal={International journal of oncology},
  year={2001},
  volume={18 6},
  pages={1293-7}
}
The region on chromosome 7q21-22 is frequently altered in several human neoplasias such as uterine leiomyoma, myeloid leukemia and breast cancer. The same region has also been linked to split hand/split foot malformation type 1 and to involutional osteoporosis. Our analysis of genes that map to this region has led to the identification of the so far unknown first exon of the homeobox gene DLX6, a mammalian homologue of the Drosophila distal-less gene. Distal-less is a downstream target of the… CONTINUE READING