The cloning of GRK7, a candidate cone opsin kinase, from cone- and rod-dominant mammalian retinas.

@article{Weiss1998TheCO,
  title={The cloning of GRK7, a candidate cone opsin kinase, from cone- and rod-dominant mammalian retinas.},
  author={Ellen R. Weiss and Dayanidhi Raman and Shigeru Shirakawa and Melissa Ducceschi and Paula Bertram and Fulton Wong and Timothy W. Kraft and Shoji Osawa},
  journal={Molecular vision},
  year={1998},
  volume={4},
  pages={27}
}
PURPOSE Desensitization in the rod cell of the mammalian retina is initiated when light-activated rhodopsin is phosphorylated by the G protein-coupled receptor kinase (GRK), GRK1, often referred to as rhodopsin kinase. A distinct kinase that specifically phosphorylates cone opsins in a similar manner has not been identified in mammals. To determine the… CONTINUE READING