The clonal evolution of metastases from primary serous epithelial ovarian cancers.

@article{Khalique2009TheCE,
  title={The clonal evolution of metastases from primary serous epithelial ovarian cancers.},
  author={Lalarukh Khalique and Ayse Ayhan and John C. Whittaker and Naveena Singh and Ian J. Jacobs and Simon A. Gayther and Susan J Ramus},
  journal={International journal of cancer},
  year={2009},
  volume={124 7},
  pages={1579-86}
}
Several models of evolution from primary cancers to metastases have been proposed; but the most widely accepted is the clonal evolution model proposed for colorectal cancer in which tumors develop by a process of linear clonal evolution driven by the accumulation of somatic genetic alterations. Various other models of cancer progression and metastasis have been proposed, including parallel evolution and the same gene model. The aim of this study was to investigate the evolution of metastases… CONTINUE READING

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PHYLIP (Phylogeny Inference Package) version 3.6

  • J. Felsenstein
  • Distributed by the author. Department of Genome…
  • 2004

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