The clinicopathological features of extensive small intestinal CD4 T cell infiltration.

@article{Carbonnel1999TheCF,
  title={The clinicopathological features of extensive small intestinal CD4 T cell infiltration.},
  author={Franck Carbonnel and H. d'Almagne and Anne Lavergne and C Matuchansky and Jean Claude Brouet and François Sigaux and Laurent Beaugerie and Judith Nemeth and Beno{\^i}t Coffin and Jacques Cosnes and Jean Pierre Gendre and Jean Claude Rambaud},
  journal={Gut},
  year={1999},
  volume={45 5},
  pages={
          662-7
        }
}
METHODS Four patients with clinicopathological features suggesting a new distinct entity defining extensive small intestinal CD4 T cell infiltration were observed. RESULTS All four patients presented with chronic diarrhoea, malabsorption, and weight loss. Biopsy specimens of the small intestine disclosed extensive and diffuse infiltration of the lamina propria by pleomorphic small T lymphocytes, which were positive for CD3, CD4, CD5, and the beta chain of T cell receptor in all three cases… CONTINUE READING

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