The clinical use of various blood compartments for cytomegalovirus (CMV) DNA quantitation in transplant recipients with CMV disease.

@article{Razonable2002TheCU,
  title={The clinical use of various blood compartments for cytomegalovirus (CMV) DNA quantitation in transplant recipients with CMV disease.},
  author={Raymund Rabe Razonable and Robert A.M. Brown and Jennie Wilson and Cynthia Groettum and Walter Karl Kremers and Mark J. Espy and Thomas F. Smith and Carlos V. Paya},
  journal={Transplantation},
  year={2002},
  volume={73 6},
  pages={968-73}
}
BACKGROUND The quantitation of cytomegalovirus (CMV) DNA is a cornerstone in the management of CMV disease in transplant recipients. However, a consensus as to what is the optimal blood compartment for the detection and quantitation of CMV DNA in peripheral blood is nonexistent. METHODS With an automated quantitative assay, we have simultaneously quantified the CMV DNA load in whole blood (WB), plasma (PL), peripheral blood leukocytes (PBL), and peripheral blood mononuclear cells (PBMC) in… CONTINUE READING
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