The clinical significance of pericentric inversion of the human Y chromosome: a rare "third" type of heteromorphism.

@article{Verma1982TheCS,
  title={The clinical significance of pericentric inversion of the human Y chromosome: a rare "third" type of heteromorphism.},
  author={Ram Singar Verma and Jorge Rodr{\'i}guez and Harvey Dosik},
  journal={The Journal of heredity},
  year={1982},
  volume={73 3},
  pages={236-8}
}
A 28-year-old normal East Indian was found to have a pericentric inversion of the Y chromosome. After reviewing the literature, it was concluded that an inverted Y chromosome does not impede the production of normal sperm and does not predispose to non-disjunction of other chromosomes in the progeny. Thus, the earlier concept of nondisjunction was rejected, and it is suggested that aberrant cases with aneuploidy and an inverted Y are fortuitous. The pericentric inverted Y is inherited from… CONTINUE READING

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