The clinical significance of neuropsychological changes following bilateral subthalamic nucleus deep brain stimulation for Parkinson's disease.

@article{Higginson2009TheCS,
  title={The clinical significance of neuropsychological changes following bilateral subthalamic nucleus deep brain stimulation for Parkinson's disease.},
  author={Christopher I. Higginson and Vicki L Wheelock and Dawn Levine and David S. King and Conrad T E Pappas and Karen A. Sigvardt},
  journal={Journal of clinical and experimental neuropsychology},
  year={2009},
  volume={31 1},
  pages={65-72}
}
Despite the clinical importance of the question, a number of methodological issues have limited firm conclusions regarding the cognitive safety of deep brain stimulation (DBS) of the subthalamic nucleus (STN) in Parkinson's disease (PD). Amongst these issues, studies have generally failed to consider the postoperative changes that occur within individual patients. This study utilized reliable change indices (RCIs) derived from a PD sample to determine the frequency of clinically significant… CONTINUE READING

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