The clinical pharmacokinetics and tolerance of enoxacin in healthy volunteers.

Abstract

In a single-dose tolerance and pharmacokinetics study, enoxacin doses ranging from 200 to 1600 mg were administered orally to 12 healthy normal volunteers. Plasma assays demonstrated rapid absorption of enoxacin with first-order elimination and a half-life averaging 3.4-6.4 h. Renal clearance accounted for approximately 40% of total body clearance of drug… (More)

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Cite this paper

@article{Wolf1984TheCP, title={The clinical pharmacokinetics and tolerance of enoxacin in healthy volunteers.}, author={R. Wolf and Robert Eberl and Attila Dunky and Natalia Ramos Mertz and T. Chang and J R Goulet and J R Latts}, journal={The Journal of antimicrobial chemotherapy}, year={1984}, volume={14 Suppl C}, pages={63-9} }