The clinical neuromuscular pharmacology of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia.

@article{Belmont1995TheCN,
  title={The clinical neuromuscular pharmacology of 51W89 in patients receiving nitrous oxide/opioid/barbiturate anesthesia.},
  author={Matthew R Belmont and Cynthia A. Lien and Steve Quessy and M M Abou-Donia and Anna Abalos and L Eppich and John J Savarese},
  journal={Anesthesiology},
  year={1995},
  volume={82 5},
  pages={1139-45}
}
BACKGROUND Atracurium is a mixture of ten stereoisomers. 51W89, one of these isomers, is a potent nondepolarizing intermediate-duration neuromuscular blocking agent. Preclinical studies have shown 51W89 to be significantly more potent than atracurium but with a similar neuromuscular blocking profile. This study was undertaken to establish the neuromuscular blocking potency and pharmacodynamics of 51W89 in patients undergoing elective surgical procedures. METHODS Ninety-nine ASA physical… CONTINUE READING
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