The clinical importance of emerging Campylobacter species

  title={The clinical importance of emerging Campylobacter species},
  author={Si Ming Man},
  journal={Nature Reviews Gastroenterology \&Hepatology},
  • Si Ming Man
  • Published 25 October 2011
  • Biology, Medicine
  • Nature Reviews Gastroenterology &Hepatology
A growing number of Campylobacter species other than C. jejuni and C. coli have been recognized as emerging human and animal pathogens. Although C. jejuni continues to be the leading cause of bacterial gastroenteritis in humans worldwide, advances in molecular biology and development of innovative culture methodologies have led to the detection and isolation of a range of under-recognized and nutritionally fastidious Campylobacter spp., including C. concisus, C. upsaliensis and C. ureolyticus… 
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An outline of the two Campylobacter groups (zoonotic and human oral), their virulence traits, and the associated illnesses including gastroenteritis is offered.
Campylobacter: from microbiology to prevention
Campylobacter spp is a commensal microorganism of the gastrointestinal tract of many wild animals, farm animals and companion animals and it is responsible for zoonoses and the transmission occurs via the fecal-oral route through ingestion of contaminated food and water.
Campylobacter Species in Poultry: Virulence Attributes, Pathogenesis, Epidemiological Typing and Zoonotic Importance
The biology of the bacterium, its survival, growth characters and the factors related to its pathogenicity and the mechanisms by which the diseases are happened in the view of the available literatures are reviewed.
Campylobacter in the Food Chain.
The Host Cellular Immune Response to Infection by Campylobacter Spp. and Its Role in Disease
The cellular immune responses across susceptible hosts to C. jejuni infection are collectively covered, along with the tissue pathology and post-infectious disorders which may develop.
Tackling Campylobacter: a Review
The costs based on the incidence, prevention and control of campylobacteriosis are high with critical impacts on surveillance programmes and hence the costs and benefits must be carefully considered.
Intestinal Infections of Campylobacter: A Review
This review aims to give an overview of the historical approaches, properties, sources and different ways of transmissions of Campylobacter spp, clarifying its pathogenesis, its treatment and the prevention against these bacteria.
Non-jejuni/coli Campylobacter Species and Related Organisms in Poultry, and Their Relevance in Human and Animal Disease
This chapter provides a survey of research on non-jejuni/coli Campylobacter spp. and related Arcobacter and Helicobacter species in poultry. The isolation and identification, clinical and veterinary


Campylobacter fetus adheres to and enters INT 407 cells.
  • L. Graham
  • Biology, Medicine
    Canadian journal of microbiology
  • 2002
Clinical isolates of C. fetus are capable of adhering, entering, and surviving within the nonphagocytic epithelial cell line, INT 407, and investigation of the role of the host cell cytoskeleton revealed that pretreatment of host cells with cytochalasin D, colchicine, vinblastine, taxol, or dimethyl sulfoxide did not impact upon C. pregnancy.
Extraintestinal Campylobacter jejuni and Campylobacter coli infections: host factors and strain characteristics.
The results suggest that either host defects or specific bacterial virulence characteristics, such as serum resistance, possibly related to length of lipopolysaccharide side chain, may be responsible for extraintestinal infections due to C. jejuni and C. coli.
Detection and quantification of 14 Campylobacter species in pet dogs reveals an increase in species richness in feces of diarrheic animals
This study demonstrates that domestic dogs can carry a wide range of Campylobacter species naturally and that there is a notable increase in species richness detectable in the diarrheic population.
Prevalence of cytolethal distending toxin (cdt) genes and CDT production in Campylobacter spp. isolated from Danish broilers.
Results confirm the common occurrence of campylobacter infection in chickens and indicate that cdt genes are commonly present in both C. jejuni and C. coli isolates from broilers, but that there are distinct differences in CDT production in these two closely related species.
Detection of Campylobacter concisus and Other Campylobacter Species in Colonic Biopsies from Adults with Ulcerative Colitis
The higher prevalence of Campylobacter genus and more specifically C. concisus and C. ureolyticus in biopsy samples from adults with UC suggests these genera of bacteria may be involved in the chronic inflammation that is characteristically seen in UC.
Campylobacter upsaliensis: Waiting in the Wings
There is now a pressing need for controlled, prospective epidemiologic studies in addition to further in-depth investigation of the pathogenesis of this enteric campylobacter to more precisely define its role in human disease.
16S rRNA gene sequences of 'Candidatus Campylobacter hominis', a novel uncultivated species, are found in the gastrointestinal tract of healthy humans.
Evidence is provided for the existence of a previously undescribed, uncultivated Campylobacter species that may be a commensal in the healthy human gut and the source of the amplicons are proposed to be 'Candidatus Campyobacter hominis'.
Wild raptors as carriers of antimicrobial-resistant Salmonella and Campylobacter strains
The prevalence and antimicrobial susceptibility of Salmonella and Campylobacter isolates from 121 wild raptors admitted to the Wildlife Rehabilitation Centre of Torreferrussa in Catalonia between October 2008 and March 2009 are described.
Campylobacter ureolyticus: an emerging gastrointestinal pathogen?
This is, to the best of the authors' knowledge, the first report of C. ureolyticus in the faeces of patients presenting with gastroenteritis and may suggest a role for this organism as an emerging enteric pathogen.
Molecular-based detection of non-culturable and emerging campylobacteria in patients presenting with gastroenteritis
SUMMARY From January 2009 to May 2010, 436 faecal samples from patients with diarrhoeal illness in Southern Ireland were identified as Campylobacter genus-positive by an automated multiplex PCR;