The clinical impact of p16 status in fine-needle aspirates of cervical lymph node metastasis of head and neck squamous cell carcinomas

  title={The clinical impact of p16 status in fine-needle aspirates of cervical lymph node metastasis of head and neck squamous cell carcinomas},
  author={J. Jakscha and I. Zlobec and C. Storck and E. Obermann and L. Tornillo and L. Terracciano and C. Fischer},
  journal={European Archives of Oto-Rhino-Laryngology},
  • J. Jakscha, I. Zlobec, +4 authors C. Fischer
  • Published 2012
  • Medicine
  • European Archives of Oto-Rhino-Laryngology
  • Lymph node involvement is prognostically the most determinant clinical factor for patients with head and neck squamous cell carcinomas (HNSCCs). Ultrasound of the neck and fine-needle aspiration (FNA) cytology is one of the first diagnostic procedures and the most accurate diagnostic staging tool for the neck. Patients with HPV-positive oropharyngeal carcinomas (OPSCC) show a significantly better prognosis when compared with HPV-negative OPSCC. P16 overexpression is accepted as surrogate marker… CONTINUE READING
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