The clinical effects of deep brain stimulation of the pedunculopontine tegmental nucleus in movement disorders may not be related to the anatomical target, leads location, and setup of electrical stimulation.

@article{Mazzone2013TheCE,
  title={The clinical effects of deep brain stimulation of the pedunculopontine tegmental nucleus in movement disorders may not be related to the anatomical target, leads location, and setup of electrical stimulation.},
  author={Paolo A M Mazzone and Stefano Sposato and Angelo Insola and Eugenio Scarnati},
  journal={Neurosurgery},
  year={2013},
  volume={73 5},
  pages={894-906; discussion 905-6}
}
BACKGROUND The pedunculopontine tegmental nucleus (PPTg) is a novel target for deep brain stimulation (DBS) in movement disorders. OBJECTIVE To clarify the relationships between the individual anatomic variations of the brainstem, the site in which the PPTg DBS is applied, and the clinical outcome in a relatively large number of patients affected by Parkinson disease or progressive supranuclear palsy. METHODS Magnetic resonance images have been used to evaluate brainstem anatomy and the… CONTINUE READING

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