The clinical effect of glutathione on skin color and other related skin conditions: A systematic review

@article{Dilokthornsakul2019TheCE,
  title={The clinical effect of glutathione on skin color and other related skin conditions: A systematic review},
  author={Witoo Dilokthornsakul and Teerapon Dhippayom and Piyameth Dilokthornsakul},
  journal={Journal of Cosmetic Dermatology},
  year={2019},
  volume={18},
  pages={728 - 737}
}
Glutathione is one of agents which is commonly used to lighten skin color in Asia as a dietary supplement. Previous studies suggest its potential effect of glutathione on skin color. However, the clinical efficacy of glutathione in oral form is still questionable due to its limited absorption and bioavailability. 

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Glutathione (GSH) is a naturally occurring thiol that has been reported to cause skin lightening in a manner for which several mechanisms have been proposed. Highest plasma concentrations are

Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women

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