The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass.

@article{Rigotti1991TheCC,
  title={The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass.},
  author={Nancy A. Rigotti and Robert M. Neer and Steven J. Skates and David B. Herzog and Samuel Nussbaum},
  journal={JAMA},
  year={1991},
  volume={265 9},
  pages={1133-8}
}
Women with anorexia nervosa have reduced bone mass and may develop fractures. Neither the pathophysiology of this osteoporosis nor its natural history is known. To study the clinical course of osteoporosis, we followed up 27 women with anorexia nervosa for a median of 25 months (range, 9 to 53 months). At study entry, cortical bone density, measured by single-photon absorptiometry of the radial shaft, was low (mean +/- SD, 0.63 +/- 0.07 g/cm2) and inversely related to the duration of amenorrhea… CONTINUE READING

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